A Case of Abscessed Pneumonia Due to COVID-19 Infection

Vorobeva O. V.
MD, PhD, Assistant Professor, Chair for General and Clinical Morphology and Forensic Medicine¹
ORCID 0000-0003-3259-3691

1 - I.N. Ulyanov Chuvash State University, Cheboksary, Russian Federation

Vorobeva Olga; e-mail: olavorobeva@mail.ru.

None declared.

The study had no sponsorship.

COVID-19 is a potentially severe acute respiratory infection caused by the SARS-CoV-2 coronavirus. The aim of the study is to describe a case of COVID-19 infection, proceeding with the addition of a bacterial infection and the development of abscess pneumonia in a young adult patient. Material and research methods. The accompanying medical documentation was studied, clinical and morphological analysis was carried out using the description of macro- and micropreparations. Research results. Patient A.E., 31 was hospitalized with a diagnosis of New coronavirus infection, severe course. Community-acquired bilateral pneumonia. Was admitted with complaints of shortness of breath, cough, fever up to febrile levels. Laboratory and instrumental tests were carried out and treatment started. However, the patient's condition worsened, respiratory failure increased, ending in lethal outcome. The postmortem examination revealed signs of bilateral pneumonia with areas of abscess formation. Histological examination revealed focal hemorrhages in the pulmonary parenchyma, merging in places and areas of necrosis of the lung tissue with the formation of «abscesses» (microabscesses). On the periphery of the area of necrosis, a well-defined shaft of granular leukocytes and congested vessels with erythrocyte sludge was noted. Signs of edema were observed in the brain; histological examination revealed perivascular, pericellular optical voids with vascular congestion, erythrocyte sludge and minor hemorrhages. Viral pneumonia caused by coronavirus and the addition of a bacterial infection, in this case staphylococcus, led to abscessed pneumonia and severe respiratory failure. Conclusion. The presented case of SARS-CoV-2 infection in a young adult patient is of particular importance and relevance, as it demonstrates an unfavorable outcome of the disease despite a young age and the absence of concomitant pathology.

COVID-19, pneumonia, microabscesses, cerebral edema

10.29234/2308-9113-2022-10-1-32-40

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