Microecological Biomarkers of the Resistance Level of the Organism in Newborns

Strakhova S. S.
MD¹

Samoukina А. М.
MD, PhD, Assistant Professor, Head, Scientific Department; Head, Chair for Hygiene and Ecology²

Аlexeeva Ju. А.
Doctor of Medicine, Professor, Head, Chair for Polyclinic Pediatrics and Neonatology²

Rodionov A. A.
MD, PhD, Assistant Professor, Chair for Public Health, Organization, Management and Economics of Healthcare«²

Strakhov М. А.
MD, PhD, Assistant Professor, Chair for Cardiovascular Surgery²

1 - Regional Clinical Perinatal Center, Tver, Russian Federation
2 - Tver State Medical University, Tver, Russian Federation

Rodionov Andrej; e-mail: andrew.rodionov@tvgmu.ru.

None declared.

The study had no sponsorship.

As a result of this study, some markers reflecting the level of body resistance and microecological disorder of the digestive tract of newborns according to the qualitative and quantitative characteristics of the microbiota of the oral cavity were identified. The study determined the bacterial and viral components, including representatives of the herpesvirus family (Epstein-Barr virus, herpes type 6, herpes simplex types 1 and 2) in combination with indicators of local immune resistance in the oral fluid in 173 newborns of I-II health groups. Determination of both herpesviruses in oral fluid of newborns and opportunistic bacterial microflora reflects the lack of general and local immune resistance. It makes it posible to classify such children as a risk group for the development of infectious pathology, in need for prescription of corrective and preventive measures.

digestive tract, oral cavity, herpesviruses, microflora

10.29234/2308-9113-2022-10-3-63-71

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